A Systematic Review of Complications from Pediatric Intraosseous Cannulation

Intraosseous (IO) infusion is a commonly used method for obtaining vascular access in emergency situations. Despite the widespread, continued use of IO cannulation pediatric subjects, high-quality systematic review literature on complications lacking. To our knowledge, this first comprehensive analysis specific to population. there are no recent meta-analyses or reviews literature. Outside intermittent case reports and retrospective prospective studies, frequently cited data topic remain sparse outdated. We identified 9.7% overall complication rate, which significantly higher than rates reported by prior particularly those including mixed cohorts children adults. This rate likely due variety factors, differences monitoring reporting between as well potential risk adult subjects. These results underscore need more standardized attributed placement. Additional larger studies safety needed, primary evidence prevalence incidence these avoid overreliance upon historical bias.